A little guy with a big heart (not to mention whiskers, a little pink nose and a really dapper wardrobe), Stuart searches for a sense of belonging and a place to call home in a decidedly supersized world. When he's adopted by the Littles, a human family, he embarks on adventures with a variety of characters--including his nemesis, family cat Snowbell--and learns the family, loyalty and friendship. The Littles, in the meantime, discover there is a little "Stuart" in all of us--the spunk, spirit and courage to be true to ourselves and follow our dreams despite the odds.