Rizwan Khan, a Muslim from the Borivali section of Mumbai, suffers from Asperger syndrome (a form of high-functioning autism complicating socialization). The adult Rizwan marries a Hindu single mother, Mandira, in San Francisco. After 9/11, Rizwan is detained by authorities at LAX who mistake his disability for "suspicious" behavior. Following his arrest, he meets Radha, a therapist who helps him deal with his situation and his affliction. Rizwan then begins a journey to meet US President Obama to clear his name.